You will be given a small dose when you first start treatment. There's now several studies showing Memantine could be of benefit in OCD … Memantine. I'm a bit nervous to take it, and there's no reviews from people who have Lyme (I also have bartonella/babesia). what dose are you on? There is some evidence that memantine can be useful in obsessive-compulsive disorder (OCD). So, it is hard to tell which of all these treatments helped most with bringing my OCD to a manageable level. Physician. I am desperate. In a randomized double-blind placebo-controlled study of memantine combined with fluoxetine published by Ghaleiha et al. Ceretropic has a good reputation for testing the composition and purity of their solutions as far as I understand, but I'd agree with you..it's best to talk to your doctor to see if they'd be willing to prescribe it to you … More patient posts reported that Namenda helped them when used for OCD Just wanted to know if anyone... constantly. I never realized how much I needed this. Press question mark to learn the rest of the keyboard shortcuts. Prior treatment resistance and the proximity between symptomatic improvement and the initiation of memantine point to its possible attenuating effect on the symptoms of OCD. Now I don't really know what to think. 1) Memantine. Do not chew, crush, or divide the capsule. Studies show that when it’s used alongside other conventional medications of OCD, the drugs can have a much better impact. The increasing evidence for the involvement of the glutamatergic system in the pathophysiology of obsessive-compulsive disorder (OCD) has led to trials of agents such as N -acetylcysteine, … 4 Responses ntb1974. 7) May Reduce the Negative Symptoms of Schizophrenia I haven't noticed any side effects. MEMANTINE/N-METHYL-D-ASPARTATE (NMDA) ANTAGONISTS; Moderate Interactions. why? Memantine helps to ease the symptoms of dementia in Alzheimer's disease. The Memantine is a Solution from Ceretropic, it is normally taken in pills but whatever floats your boat. Which is better for OCD: Memantine or Namenda? At times I can’t get it to stop. I take 10 mg twice a day. OCD, anxiety or both?. It's also the first medicine that I took that affects dopamine pathways (as opposed to seretonon). u/Rirt. Has anyone tried this yet? Memantine is a moderate-affinity uncompetitive NMDA receptor antagonist that is approved in the U.S. for the treatment of Alzheimer’s disease. It really... Hello. I really recommend Moclobemide and Memantine for anyone who suffers from OCD and SA. I do not remember if there were any bad side effects. Have anyone here tried memantine for pure o ocd ? To be honest with you I take Wellbutrin which is not the first line drug for OCD but it works for me so everyone is different. The mean … A subreddit dedicated to discussion, articles, and images regarding OCD. Cookies help us deliver our Services. I also use Xanax when I need to. Twenty-two subjects receiving memantine in addition to standard care were matched with 22 OCD inpatient controls. Memantine can help with decreasing the symptoms of OCD but not on its own. It was recently FDA approved for OCD. If anyone has information on or experience with any of the above medications, would you please share that with me? I tried higher doses, but it just made me want to sleep for the whole day. Answer Question. A second drug that is already available and affects how neurons respond to glutamate is memantine (Namenda®). Obsessive compulsive disorder (OCD) [9] Generalized anxiety disorder [10] Addiction therapy [11] ADHD [12] All of these benefits have received far less academic attention than the Alzheimer’s disease and senile dementia research. I also take zoloft at 300mg. Memantine. Stewart et al. Memantine. I don't abuse my friends and family, my anxiety is significantly lessened, and I can act normally in social situations. Can anyone provide some insight? I don’t know what this is. In 2013, Rodriguez and colleagues published their results from that first clinical trial of ketamine in OCD patients. Adding memantine to a selective serotonin reuptake inhibitor improved outcomes in patients with moderate-to-severe OCD. New comments cannot be posted and votes cannot be cast. whopper Former jolly good fellow. If a patient fails to take memantine for several days, dosing may need to be resumed at lower doses and re-titrated. Sorry if this is of absolutely no help to you. The trial randomized 15 patients with OCD to ketamine or placebo. It just makes me happier in general...more human, more personalable. It would be nice if it was somehow longer lasting. How long did it take to take effect? Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. This will gradually be increased over the following few weeks. This is in accordance with a few previous studies. The selegiline combination is best left to the advanced Nootropic users. Inositol was one of the things I took in my anxiety healing phase, but I did not suffer from OCD. It helps reduce dementia symptoms, but it doesn’t cure Alzheimer’s. Drugs that act on ionotropic receptors or modulate glutamate neurotransmission, such as riluzole, lamotrigine and memantine demonstrated improvements in symptoms when used as adjunctive therapy in refractory OCD. Memantine … Memantine appears to work by regulating the activity of glutamate, one of the brain's specialized messenger chemicals, which may play a role in OCD. As in the case of riluzole … Anyone on this glutamate modulater? 15+ Year Member. r/OCD. “I take 10mg memantine daily for mood instability related to bipolar disorder type 2. In a clinical trial on 38 patients, approximately 89% of those combining the SSRI fluvoxamine with memantine no longer had OCD symptoms after eight weeks compared with 32% … I was on memantine long time ago for OCD. Memantine … I have been on it for 4 months now, and for the first time in many years I actually feel like I have a future. I've been on memantine for 5 years. Take one dose every day, at the same time of day each day. 2. I've been on it for 12 days and have many side effects , i feel not able to remember thing , impairing of my study which requires so much memorizing and analytics process , Do you think these side effects will subside ? The association of OCD-schizotypal comorbidity with the beneficial effect of memantine is noteworthy in view of a pertinence of glutamatergic dysfunction in both OCD … It has almost completely cured me. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Again, memantine was well tolerated and there were no serious adverse effects. I am in... also take trintillex and resulti. in 2012, patients with moderate to severe OCD taking memantine and fluoxetine were more likely … Related to ocd it was worsening in the first days , now it's moderate. Obsessive-compulsive disorder (OCD) affects an estimated 1% of the US population, ... memantine, or n-acetyl-cysteine may be effective for some patients. Yes. In those patients who were given ketamine, the effect was immediate. It’s... guidance from anyone who may have experience with Prozac long term. Memantine is not FDA approved for OCD, but is approved for the treatment of Alzheimer's Disease. While these promising studies have prompted community members and nootropics enthusiasts to try the drug themselves, the benefits aren’t set in stone. What concerns me is people saying that memantine is the … The pro: it helps fight OCD with little side effects. These medications may cause some risk when taken together. Thank you for reply , how long have you been using it ? 2. r/OCD: A subreddit dedicated to discussion, articles, and images regarding OCD. Follow - 1. I take 10 mg twice a day. Does anyone with OCD have anyother suggestions for medications for OCD? Anyone ever tried memantine? Another study reported that 89% of the patients who received memantine along with conventional treatments resolved their OCD symptoms after eight weeks . You might try posting on the Anxiety forum where there is more activity at the moment to see if anyone has tried these medications for anxiety. Immediate-release tablets: May administer with or without food. I've been on memantine for 5 years. All patients in the study will receive memantine; no one will receive placebo. Have anyone here tried memantine for pure o ocd … or did it just not work? Several case reports and two recent open-label case series suggest that the addition of memantine to standard medication therapy can benefit both children and adults with OCD. Perhaps ketamine could help regulate OCD symptoms as well as depression. Hey everyone, I have tried many different ocd drug therapies, but have yet to try a glutamate modulating therapy such as Memantine , Riluzole (Rilutek), N-acetyl cysteine, or amantadine. Read 4 Responses. Archived. Feeling that I will never really get the Cognitive Behavioural help that I need. Press question mark to learn the rest of the keyboard shortcuts . I usually take one dose when I wake up and one dose when I get home from work. However, when I started it, I was also in the process of switching my main antidepressant from Anafranil (generic name is clomipramine) to Zoloft (generic name is sertraline) and was also undergoing intensive ERP at the OCD … How long does it take until I can stop giving into my ocd and compulsions and feel okay. Any bad side effects? All of which I have … I am on it now. Thanks … Some … 2 years ago. I haven't noticed any side effects. conducted a further single-blind, case–control study of memantine in OCD inpatients. These case reports and open-label studies have shown the beneficial effect of memantine in case of OCD even in refractory and pediatric OCD. Press J to jump to the feed. The use of memantine in OCD has been demonstrated in open-label trials and in two … Close. Please read below for more information and resources about about OCD and what this subreddit is! and seroquel 900mg XR. Thanks. Press J to jump to the feed. The exact dose I don't know, but anyone suffering from OCD, please take some time and read about Inositol as a treatment for it and see what you think. In this study the investigators are recruiting patients to receive the drug memantine, which is thought to modulate the neurotransmitter glutamate, added to whatever other OCD medications they are … 9 . Posted by. By using our Services or clicking I agree, you agree to our use of cookies. You can take memantine either before or after meals. However, when I started it, I was also in the process of switching my main antidepressant from Anafranil (generic name is clomipramine) to Zoloft (generic name is sertraline) and was also undergoing intensive ERP at the OCD Institute at McLean Hospital in Belmont, MA. It seems to be working well at keeping my OCD under control. Extended-release capsules: May administer with or without food. I had to increase it to 45mg. Medications that target glutamate hold promise for ameliorating symptoms for those patients continuing to suffer from OCD. And each time, I feel like I took the pill in the nick of time. User account menu. It seems to be working well at keeping my OCD under control. If so, did it work? I suffered from anxiety, panic and agoraphobia. Questions about Memantine - posted in Brain Health: Hi, I'd like to get some answers from people who have researched memantine and know a lot about it. Feb 8, 2004 7,143 2,057 Visit site Status Attending Physician May 20, 2012 #28 I haven't tried Memantine for OCD. I did some searching on the forum and read some good and some bad stuff. This antagonist, which has fewer side effects than other NMDA antagonists, is believed to work by competing with magnesium in the synapse, which inhibits the prolonged … i take abilify for refractory OCD. May have patient … I have used it for pseudobulbar palsey and it worked. No other SSRI helped like luvox or zoloft, … Because NAA is found primarily on neuronal axons in the brain, 9 perhaps the neuroprotective effect of memantine can be measured by quantifying the change in NAA concentrations in … Thanks. Add-on memantine was well tolerated and resulted in clinically significant reduction of OCD symptom severity. I am the author of Overcoming OCD: A Journey to Recovery (Rowman & Littlefield, January 2015) and have my own blog about OCD at ocdtalk.wordpress.com. Memantine's suggested neuroprotective effect 2,8 may also increase brain levels of the neuronal marker, N-acetyl aspartate (NAA). Living with a family member who is "content" with having Mys... feeling bad, need support (disorders suddenly returned). log in sign up. Anyone stop taking? It has changed my life for the better. I was prescribed memantine by my LLMD for severe, severe memory loss (both short term and long term). Oral Solid Formulations. Faculty. The con: It wears off very quickly (within hours). get from my OCD is when I take clonazapam which as we know you cannot take everyday. For me, there are pros and cons. (take my words on pshysiology with a grain of salt, im still trying to connect the dots, there is lots of research to be done on OCD and the brain in general) TLDR: i think Ashwagandha is really helpful with controlling obsession triggers and general anxiety ( there is also some research behind it, you can look it up on Examine) also vit C, … Memantine oral tablet is a prescription medication used to treat moderate to severe dementia caused by Alzheimer’s disease. Memantine, a medication used for Alzheimer’s disease, blocks NMDA receptors, which reduces glutamate’s effects in the brain.